LES BIENFAITS DE L'AIL NOIR

L’ail noir, aussi appelé ail vieilli, a fait l’objet de plusieurs centaines d’études
scientifiques partout à travers le monde dû à ses bénéfices pour la santé. Pour permettre une meilleure compréhension des différentes propriétés de l’ail, les découvertes scientifiques ont été classées en fonction de leur plus haut niveau de recherche :

Activités anti-cancer

Améliore la résistance à l’insuline

Bénéfique à la guérison des blessures

Diminue le stress psychologique

Gastroprotecteur

Neuroprotecteur

Potentiel anti-obésité

Propriétés anti-inflammatoires

Réduit la fatigue physique

ANIMAL

Antimicrobien

Plus d’antioxydants et de polyphénols que dans l’ail frais

LABORATOIRE

Diminue les risques cardiovasculaires

Contrôle de la pression sanguine

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LABORATOIRE

Botas J, et al. A Comparative Study of Black and White Allium sativum L.: Nutritional Composition and Bioactive Properties. Molecules. 2019 Jun 11;24(11). pii: E2194

Elosta A, et sl. Aged garlic has morepotent antiglycation and antioxidant properties compared to fresh garlic extract in vitro. Sci Rep. 2017 Jan 4;7:39613

Toledano-Medina MA, et al. Evolution of some physicochemical and antioxidant properties of black garlic whole bulbs and peeled cloves. Food Chem. 2016 May 15;199:135-9

ANIMAL

Cemil B, et al. Aged Garlic Extract Attenuates Neuronal Injury in a Rat Model of Spinal Cord Ischemia/Reperfusion Injury. J Med Food. 2016 Jun;19(6):601-6

Cemil B, et al. Effects of the aged garlic extract on spinal cord injury model in rat. Ulus Travma Acil Cerrahi Derg. 2012 Nov;18(6):463-8

Chauhan NB, Sandoval J. Amelioration of early cognitive deficits by aged garlic extract in Alzheimer's transgenic mice. Phytother Res

Dong M, et al. Aged black garlic extract  inhibits HT29 colon cancer cell growth via the PI3K/Akt signaling pathway. Biomed Rep

Ejaz S, et al. Effect of aged garlic extract on wound healing: a new frontier in wound management. Drug Chem Toxicol. 2009;32(3):191-203

El-Ashmawy NE, et al. Gastroprotective effect of garlic in indomethacin induced gastric ulcer in rats. Nutrition. 2016 Jul-Aug;32(7-8):849-54

Fallah-Rostami F, et al. Immunomodulatory activity of aged garlic extract against implanted fibrosarcoma tumor in mice. N Am J Med Sci. 2013 Mar;5(3):207-12

Hwang KA, et al. Low temperature-aged garlic extract suppresses psychological stress by modulation of stress hormones and oxidative stress response in brain. J Chin Med Assoc. 2019 Mar;82(3):191-195

Jeong JH, et al. Ameliorating effects of aged garlic extracts against Aβ-induced neurotoxicity and cognitive impairment. BMC Complement Altern Med. 2013 Oct 18;13:268.

Jikihara H, et al. Aged garlic extract inhibits 1,2-dimethylhydrazine-induced colon tumor development by  suppressing cell proliferation. Oncol Rep. 2015 Mar;33(3):1131-40

Katsuki T, et al. Aged garlic extract has chemopreventative effects on 1,2-dimethylhydrazine-induced colon tumors in rats. J Nutr. 2006 Mar;136(3 Suppl):847S-851S

Kim DG, et al. Antiinflammatory Effects of Functionally Active Compounds Isolated from Aged Black Garlic. Phytother Res. 2017 Jan;31(1):53-61

Kim MJ, et al. Aged black  garlic exerts anti-inflammatory effects by decreasing no and proinflammatory cytokine production with less cytoxicity in LPS-stimulated raw 264.7 macrophages  and LPS-induced septicemia mice. J Med Food. 2014 Oct;17(10):1057-63

Lv Y, et al. Anti-cancer activities of S-allylmercaptocysteine from aged garlic. Chin J Nat Med. 2019 Jan;17(1):43-49

Maeda T, et al. Aged garlic extract ameliorates fatty liver and insulin resistance and improves the gut microbiota profile in a mouse model of insulin resistance. Exp Ther Med. 2019 Jul;18(1):857-866

Matsuura N, et al. Aged garlic extract inhibits angiogenesis and proliferation of colorectal carcinoma cells. J Nutr. 2006 Mar;136(3 Suppl):842S-846S

Morihara N, et al. H. Aged garlic extract ameliorates physical fatigue. Biol Pharm Bull

Morihara N, et al. Aged garlic extract suppresses inflammation in apolipoprotein E-knockout mice. Mol Nutr Food Res. 2017 Oct;61(10)

Nam H, et al. Aged black garlic extract regulates lipid metabolism by inhibiting lipogenesis and promoting lipolysis in mature 3T3-L1 adipocytes. Food Sci Biotechnol. 2017 Dec 12;27(2):575-579

Nillert N, et al. Neuroprotective Effects of Aged Garlic Extract on Cognitive Dysfunction and Neuroinflammation Induced by β-Amyloid in Rats. Nutrients. 2017 Jan 3;9(1). pii: E24

Nurmasitoh T, et al. The effects of black garlic on the working memory and  yramidal cell number of medial prefrontal cortex of rats exposed to monosodium glutamate. Drug Chem Toxicol. 2018 Jul;41(3):324-329

Thorajak P, et al. Effects of Aged Garlic Extract on Cholinergic, Glutamatergic and GABAergic Systems with Regard to Cognitive Impairment in Aβ-Induced Rats. Nutrients. 2017 Jul 1;9(7). pii: E686

Wang X, et al. Aged black garlic extract induces inhibition of gastric cancer cell growth in vitro and in vivo. Mol Med Rep. 2012 Jan;5(1):66-72

You BR, et al. Anti-inflammatory effect of aged black garlic on 12-O-tetradecanoylphorbol-13-acetate-induced dermatitis in mice. Nutr Res Pract. 2019 Jun;13(3):189-195

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Liu J, et al. Black Garlic Improves Heart Function in Patients With Coronary Heart Disease by Improving Circulating Antioxidant Levels. Front Physiol. 2018 Nov 1;9:1435

Mahdavi-Roshan M, et al. Does Garlic Supplementation Control Blood Pressure in Patients with Severe Coronary Artery Disease? A Clinical Trial Study. Iran Red Crescent Med J. 2016 Aug 24;18(11):e23871

Morihara N, et al. Aged Garlic Extract Suppresses the  Development of Atherosclerosis in Apolipoprotein E-Knockout Mice. J Nutr. 2016 Feb;146(2):460S-463S

Pérez-Torres I, et al. Effect of the Aged Garlic Extract on Cardiovascular Function in Metabolic Syndrome Rats. Molecules. 2016 Oct 26;21(11)

Ried K, et al. Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension: a randomised controlled trial. Maturitas. 2010 Oct;67(2):144-50

Ried K, et al. Aged garlic extract reduces blood pressure in hypertensives: a dose-response trial. Eur J Clin Nutr. 2013 Jan;67(1):64-70

Ried K, et al. The effect of aged garlic extract on blood pressure and other cardiovascular risk factors in uncontrolled hypertensives: the AGE at Heart trial. Integr Blood Press Control. 2016 Jan 27;9:9-21

Seo DY, et al. Independent beneficial effects of aged garlic extract intake with regular exercise on cardiovascular risk in postmenopausal women. Nutr Res Pract.  2012 Jun;6(3):226-31

Zeb I, et al. Aged garlic extract and coenzyme Q10 have favorable effect on inflammatory markers and coronary atherosclerosis progression: A randomized clinical trial. J  Cardiovasc Dis Res. 2012 Jul;3(3):185-90

Zini A, et al. The Efficacy of Aged Garlic Extract on Gingivitis - A Randomized Clinical Trial. J Clin Dent

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